Homology-Directed Repair: The Path Forward
1-Day Workshop
Meliá Lebreros Hotel, Seville
Monday 6 October 2025
Welcome & meeting objectives
​Gene editing based on homology-directed repair (HDR) remains one of the most versatile ways to edit the human genome. This workshop will provide an overview of the current state of the HDR field, setting the stage for in-depth discussions on how to advance and optimize HDR technologies across all nuclease platforms. Attendees will gain insights into recent progress in enhancing HDR efficiency, determining editing specificity, applying HDR in diverse cell types, and the workshop will also present the latest clinical data on HDR-edited cells. Join us to explore where the field stands today and collaboratively identify new strategies to drive HDR technology forward.
Organising committees:
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Matthew Porteus, Stanford University, Stanford, USA
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José Carlos Segovia Sanz, CIEMAT-CIBERER/IIS-FJD, Madrid, Spain
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David Rawlings, University of Washington, Seattle, USA
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Paula Cannon, University of Southern California, Los Angeles, USA
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Ayal Hendel, Bar-Ilan University, Ramat-Gan, Israel
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Justin Eyquem, University of California San Francisco, San Francisco, USA
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Alessia Cavazza, University College London, London, UK
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Rasmus Bak, Aarhus University, Aarhus, Denmark
Programme and speakers
The programme will be available shortly.
This is the speaker list
​Rasmus Bak
Alessia Cavazza
Raffaella Di Micco
Justin Eyquem
Nick Haining
Ayal Hendel
Marcello Maresca
Luigi Naldini
Matthew Porteus
David Rawlings
Jose Carlos Segovia Sanz
Julien Valton
Registration Guidelines
Abstract submissions
We encourage you to submit an abstract for both the HDR Workshop and the ESCGT Congress simultaneously (if you ticked the box on the ESGCT submission there is no need to submit again for this event, but if you did not see this tickbox please submit your abstract again when registering to this event). Each will be reviewed separately. It is possible to that your poster will be accepted for both meetings, however, only one oral presentation will be allowed.
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Abstract submission will close on Friday 29 August 2025. After the abstract submission has closed, your abstract will be sent for review by our panel of moderators. Please note the notification email will be sent to the email given when you submitted your abstract.
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Check our Abstract Submission Guidelines and Abstract Submission Terms & Conditions before submitting your abstract.
Payment guidelines
Payment by credit or debit card is preferred and will ensure your registration is activated immediately; our payment services are handled by STRIPE. Please note that you do NOT need to have an account with STRIPE in order to use this service.
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Payments by bank transfer must be received within 2 weeks of your invoice date.
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All unpaid registrations for which correspondence has not been received 10 days before the event will be deleted.
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Invoices
Invoices are available to view and download from the 'Orders' page in your online registration account. PLEASE NOTE that no separate invoices will be created or sent by the congress office.
Once payment has been received you will be sent a payment confirmation email.
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Cancellations and substitutions
Partial refunds are offered for cancellations received up to 20 days before the event. Please note the percentage of refund available is dependent on the amount of notice received. See our Registration Cancellation Policy outlined in the Registration Terms and Conditions for full details.
You may transfer your registration to someone else within your organisation. Please request this in writing to christina@luminaeu.com
All financial questions and queries can be directed to christina@luminaeu.com
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Terms and Conditions
Read our registration terms and conditions.
Venue, Travel and Accommodation
Venue
Nerja-Jerez Room, Meliá Lebreros Hotel,
Luis Morales, 2
Seville
Accommodation
BCO Congresos has been designated as the official accommodation agency for the 32nd Annual Congress of the European Society of Gene and Cell Therapy.
Book your accommodation now at: https://esgct2025.bcocongresoshotels.com
For group bookings of 5 or more rooms, please contact BCO Congresos directly for availability and conditions.
Contact by email: esgcthotels@bcocongresos.com
Or by phone: +34 938 823 878
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Important note:
Please be aware of counterfeit websites and unauthorised agencies that may pose as an official partner.
We recommend using the official housing agency, BCO Congresos, to book rooms for the 32nd Annual Congress of the European Society of Gene and Cell Therapy.
How to get there
From the central train station: The Meliá Lebreros Hotel is 900m (a 15 minute walk) from Seville's central train station (Sevilla-Santa Justa Station).
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From the airport: The Hotel is 9km from Seville Airport. The EA bus line connects the Airport with the city centre, stopping at Santa Justa Station (approx. 35 minutes journey time). There is a single taxi rank at the airport T1 Level 0 for both drop off and collection. Seville city taxis apply a flat airport fare for all services between the airport and the city. More information >
Sponsors
Sponsorship opportunities
We can offer a variety of opportunities for sponsoring the HDR Workshop. Please contact Liz at liz@luminaeu.com for the sponsor prospectus and further details.
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